I know you, you’re sitting at your computer thinking “Blasphemery, I cut my baby teeth on Archbishop Lazarus. I did so many Mephisto runs that the Durance of Hate is practically my second home. There’s nothing you can possibly tell me about the world of Sanctuary that I don’t already know.” Well mister, you’ve got quite an attitude. Diablo III is a much different beast than the previous titles, and there are quite a few things that even an experienced player like yourself might miss out on due to being caught up in the excitement of this decade-in-the-making title.

TURN ON ELECTIVE MODE AND ADVANCED TOOLTIPS. This eliminates some of the obligatory dumbing down that we have in modern video games, lets you use any skills you want in any slot, and helps in figuring out how to gear your characters. This should be the very first thing you do when you start up D3. Well, after you know, making your awesome new Hero.

PICK UP GOLD. For the love of Tyreal, pick up every single gold pile that drops on the ground, it’s not worthless anymore! White/grey items sell for about 1-10 gold each and do nothing but clog up your inventory, so picking up gold piles is actually the best way to acquire currency! You don’t even have to click it! Just walk over it! Stop being lazy, you need gold! Why
do you need gold you ask? Well…

To upgrade your stash 7 slots: (10k each.)
To buy another stash tab: (100k, 200k, respectively.)
To upgrade your blacksmith
To craft blacksmith items
To upgrade your jewelcrafter
To upgrade the quality of jewels
To buy vendor items
And of course to buy items off the fancy new Auction House.
(Oh and you can also sell gold on the Real Money Auction House once it’s implemented.)